Related Experiment Video

Updated: Dec 18, 2025

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
08:33

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay

Published on: June 25, 2019

8.5K

Timing Is Everything: The T-Cell Response to α-Synuclein Is Maximal in Early Parkinson's

Antonina Kouli1, Caroline H Williams-Gray1

  • 1Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

Movement Disorders : Official Journal of the Movement Disorder Society
|June 20, 2020
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Parkinson's diseaseT cellsimmune systemα-synuclein

More Related Videos

Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein
14:45

Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein

Published on: July 29, 2022

6.4K
Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
12:01

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein

Published on: May 30, 2015

11.1K

Related Experiment Videos

Last Updated: Dec 18, 2025

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
08:33

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay

Published on: June 25, 2019

8.5K
Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein
14:45

Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein

Published on: July 29, 2022

6.4K
Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
12:01

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein

Published on: May 30, 2015

11.1K

Related Concept Videos

Neural Regulation01:37

Neural Regulation

42.9K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
42.9K
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

1.5K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
1.5K
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

839
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
839

Articles linked to this work by shared authors, journal, and citation graph.

Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society·2025

"Recommendations for clinical study protocols for immune and inflammatory profiling in Parkinson's disease".

NPJ Parkinson's disease·2025

Pharmacological and pupillary evidence for the noradrenergic contribution to reinforcement learning in Parkinson's disease.

Communications biology·2025

Beta-adrenoceptor drugs and progression to Parkinson's disease milestones in a large pooled incident cohort.

NPJ Parkinson's disease·2025

Genetic Analysis of the X Chromosome Associates Loci with Progression of Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society·2025

The profile of gastrointestinal dysfunction in prodromal to late-stage Parkinson's disease.

NPJ Parkinson's disease·2025

Longitudinal Iron Changes in the Substantia Nigra of Early-Stage Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society·2026

Spatiotemporal Tau Accumulation and its Clinical Impact on Progressive Supranuclear Palsy: Longitudinal Florzolotau (18F) Positron Emission Tomography.

Movement disorders : official journal of the Movement Disorder Society·2026

Distinct Spatiotemporal Patterns of Dopaminergic and Metabolic Imaging in De Novo Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society·2026

Fifteen-Year Outcomes of Bilateral Pallidal Stimulation in Isolated Generalized Dystonia: Characterization of Therapeutic Response and Emergence of Parkinsonism.

Movement disorders : official journal of the Movement Disorder Society·2026

Dopamine-Deficiency-Related Reorganization of the Somatomotor Network in Prodromal and Early Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society·2026

The Effect of LRRK2 and GBA1 Mutations on Survival in Early- and Late-Onset Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society·2026

Multiomic analysis identifies T cell subsets and mechanisms of epithelial interaction in idiopathic pulmonary fibrosis.

JCI insight·2026

[Fulminant blood sugar increase - a rare but life-threatening course].

Praxis·2026

Large Calyceal Diverticulum Mimicking a Solid Renal Mass in a Patient Undergoing 68Ga-DOTATATE PET/CT.

Clinical nuclear medicine·2026

Impact of burosumab on kinetics of intact FGF23 values after the removal of a causative tumor in a patient with tumor-induced osteomalacia.

JBMR plus·2026

Primary Mediastinal T-Lymphoblastic Lymphoma With Airway Stenosis Diagnosed Using Endobronchial Ultrasound-Guided Transbronchial Mediastinal Cryobiopsy: A Case Report.

Respirology case reports·2026

The microenvironment in canine mast cell tumors: association between tumor-associated tissue eosinophilia and histological grade.

Frontiers in veterinary science·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us