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Updated: Dec 18, 2025

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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Spinal heat shock protein 27 participates in PDGFRβ-mediated morphine tolerance through PI3K/Akt and p38 MAPK

Zheng Li1, Xiaoling Peng1, Xiaoqian Jia1

  • 1Department of Anesthesiology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.

British Journal of Pharmacology
|June 20, 2020
PubMed
Abstract

Keywords:
HSP27PDGFRβmorphine tolerancesignaling pathway

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