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Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
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Personal activity intelligence and mortality - Data from the Aerobics Center Longitudinal Study.

Javaid Nauman1, Xuemei Sui2, Carl J Lavie3

  • 1Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; Institute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates; Healthy Living for Pandemic Event Protection (HL - PIVOT) Network, Chicago, IL, USA.

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Achieving 100 weekly Personal Activity Intelligence (PAI) points is linked to a lower risk of all-cause and cardiovascular disease mortality, potentially adding over 4 years to life expectancy.

Keywords:
Activity metricCardiovascular diseaseExerciseMortalityPhysical activity

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Area of Science:

  • Cardiovascular Health
  • Preventive Medicine
  • Exercise Physiology

Background:

  • Personal Activity Intelligence (PAI) is a novel metric translating heart rate data into a weekly score.
  • Previous PAI studies were limited to Norwegian populations, questioning generalizability.

Purpose of the Study:

  • To investigate the association between PAI and total and cause-specific mortality in a large US cohort.
  • To assess the impact of PAI on longevity and cardiovascular disease (CVD) risk.

Main Methods:

  • Analysis of the Aerobics Center Longitudinal Study (ACLS), a prospective cohort of 56,175 participants (1974-2002).
  • Participants were categorized into 4 weekly PAI groups (0, ≤50, 51-99, ≥100).
  • Outcomes assessed included total mortality, CVD mortality, and ischemic heart disease (IHD) mortality over a median 14.9-year follow-up.

Main Results:

  • A weekly PAI score of ≥100 was associated with a 21% lower risk of all-cause mortality and a 30% lower risk of CVD mortality compared to inactive individuals (0 PAI).
  • Higher PAI scores showed significant reductions in CVD and IHD mortality, particularly in men and women with known CVD risk factors.
  • Participants achieving ≥100 PAI weekly lived an average of 4.2 years longer than inactive individuals.

Conclusions:

  • PAI is a valuable metric associated with reduced long-term mortality from all causes, CVD, and IHD.
  • Recommendations for PAI thresholds can be incorporated into clinical practice and personal health assessments for improved outcomes.
  • This study supports the use of PAI for promoting cardiovascular health and longevity in diverse populations.