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Updated: Dec 17, 2025

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Published on: December 4, 2020
Recurrent urinary tract infections: from pathogenesis to prevention
Carlos Pigrau1, Laura Escolà-Vergé2
1Servicio de Enfermedades Infecciosas, Hospital Universitario Vall d'Hebron; Departamento de Medicina, Universidad Autónoma de Barcelona, Barcelona, España; Red Española de Investigación en Patología Infecciosa (REIPI RD16/0016/0003); Consultoría Medicina-Enfermedades-Infecciosas, Clínica Creu Blanca, Barcelona, España.
Abstract:
Urinary tract infections are highly prevalent among women and when they are recurrent they can lead to patient discomfort and high healthcare costs, and they represent one of the most frequent causes of antibiotic consumption. There are several options to prevent RUTI which include both antibiotic treatment (continuous or postcoital antibiotic prophylaxis) and non-antibiotic measures (hygienic measures, vitamin D, blueberries, D-mannose, probiotics, oestrogens, vaccines, intravesical instillations), but with different levels of evidence, sometimes of poor quality, and therefore new randomized and comparative studies are needed to choose the best strategy.
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