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Related Experiment Videos

Peritoneal fluid analysis in ponies after abdominal surgery.

E M Santschi1, C B Grindem, L P Tate

  • 1Department of Food Animal and Equine Medicine, School of Veterinary Medicine, North Carolina State University, Raleigh 27606.

Veterinary Surgery : VS
|January 1, 1988
PubMed
Summary

Post-laparotomy, ponies showed elevated peritoneal fluid leukocytes and protein for six days. Blood counts revealed a temporary stress leukogram, with plasma fibrinogen peaking on day 4, indicating surgical stress and inflammation.

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Area of Science:

  • Veterinary Surgery
  • Equine Medicine
  • Surgical Pathology

Background:

  • Exploratory laparotomy is a common surgical procedure in horses.
  • Monitoring post-operative peritoneal fluid and blood parameters is crucial for assessing recovery.
  • Understanding the physiological response to abdominal surgery in ponies is important for clinical practice.

Purpose of the Study:

  • To evaluate peritoneal fluid and systemic hematological changes following exploratory laparotomy in ponies.
  • To characterize the inflammatory and stress responses in ponies after abdominal surgery.

Main Methods:

  • Ten student surgery ponies underwent exploratory laparotomy.
  • Abdominal paracentesis was performed pre- and post-operatively for six days.
  • Complete blood counts (CBCs) and plasma fibrinogen levels were analyzed pre- and post-operatively.

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  • Necropsy was performed after euthanasia.

    • Main Results:

    • Post-operative peritoneal fluid showed elevated total leukocyte count and total protein for six days.
    • Complete blood counts revealed a transient stress leukogram on day 1, normalizing by day 4.
    • Mean plasma fibrinogen levels peaked on postoperative day 4.

    Conclusions:

    • Exploratory laparotomy in ponies induces a sustained inflammatory response in peritoneal fluid.
    • Systemic inflammatory markers, like CBCs, normalize relatively quickly, but fibrinogen remains elevated longer.
    • These findings provide reference data for post-operative monitoring in equine abdominal surgery.