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Types of Membrane Protrusions01:28

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Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
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Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
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Characterization of embryonic surface ectoderm cell protrusions.

Cecília G Magalhães1, Maraysa de Oliveira-Melo2, Mario C Cruz3

  • 1Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.

Developmental Dynamics : an Official Publication of the American Association of Anatomists
|June 21, 2020
PubMed
Summary
This summary is machine-generated.

Embryonic cell protrusions differ between chick and mouse embryos, with longer, more stable ones found in areas without shape changes. These dynamics may aid intercellular communication in developing head tissues.

Keywords:
chick embryolens developmentmouse embryoperiplacodal cellsprotrusionsurface ectoderm

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Area of Science:

  • Developmental biology
  • Cell biology
  • Embryology

Background:

  • Embryonic development involves complex cell behaviors shaping tissues.
  • Cell protrusions are crucial for tissue morphogenesis, cell communication, and signaling.
  • Understanding protrusion dynamics is key to deciphering developmental processes.

Purpose of the Study:

  • To compare protrusion dynamics in the surface ectoderm of chick and mouse embryos.
  • To investigate differences between cells around the lens placode and other head regions.

Main Methods:

  • Live imaging of chick and mouse embryonic development.
  • Detailed analysis of cell protrusion dynamics.
  • Comparative study of protrusion characteristics across different embryonic regions.

Main Results:

  • Mouse embryonic protrusions are longer than chick.
  • Protrusions in stable regions are longer and more stable than those near the invaginating lens placode.
  • Intercellular trafficking of membrane puncta observed in protrusions of both species.

Conclusions:

  • Embryonic protrusion dynamics are adaptable to their environment.
  • Protrusions likely play a role in intercellular communication within embryonic head epithelia.