Hodgkin's disease occurring in a patient treated successfully for Goodpasture's syndrome

The case is presented of a 19 year-old male who was diagnosed as suffering from Goodpasture's syndrome, treated with reducing doses of prednisone and chlorambucil for 12 months and who developed Hodgkin's disease 16 years later. Various postulates to explain the occurrence of Hodgkin's disease in this patient are proposed, and the possible association between Goodpasture's syndrome and Hodgkin's disease is discussed with reference to iatrogenic, genetic, environmental and immunological factors.