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Updated: Dec 17, 2025

Multifactorial Assessment of Motor Behavior in Rats after Unilateral Sciatic Nerve Crush Injury

Multifactorial Assessment of Motor Behavior in Rats after Unilateral Sciatic Nerve Crush Injury

Published on: July 31, 2021

Amputation in crush syndrome: A case report.

María Camila Arango-Granados¹, Diego Fernando Cruz Mendoza¹, Alexander Ernesto Salcedo Cadavid¹

¹Fundación Valle del Lili, Cra. 98 ## 18-49, Cali, Valle del Cauca, Colombia; Universidad Icesi, Cl. 18 #122-135, Facultad de Medicina, Cali, Valle del Cauca, Colombia.

International Journal of Surgery Case Reports

|June 22, 2020

Summary

Early amputation may benefit patients with crush syndrome (CS) experiencing progressive deterioration despite aggressive treatment. This case highlights the potential value of considering amputation early, even with questionable limb viability, to improve patient outcomes.

Area of Science:

Trauma Surgery
Emergency Medicine
Critical Care

Background:

Crush syndrome (CS) presents significant morbidity and mortality due to severe rhabdomyolysis, reperfusion injuries, electrolyte imbalances, and organ failure.

Keywords:

Amputation Crush injuries Crush syndrome Fasciotomy Rhabdomyolysis

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The therapeutic role of fasciotomy for compartment syndrome in crush injuries remains debated, and patient-centered benefits of early amputation are not well-established.