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COVID-19: Overview of Rheumatology Fellows
Andrea Garcia-Guillén1, Sicylle Jeria1, David Lobo-Prat1
1Servei de Reumatologia. Hospital de la Santa Creu i Sant Pau, Barcelona, España.
Insights
Rheumatologists utilized their expertise and experience with arthritis medications to treat patients during the COVID-19 pandemic. This approach addressed the lack of specific treatments and clinical trials for the novel coronavirus disease.
Area of Science:
- Infectious Diseases
- Rheumatology
- Immunology
Background:
- The global spread of SARS-CoV-2 (COVID-19) since December 2019 has presented a significant health emergency.
- The pandemic highlighted vulnerabilities in global health systems, necessitating rapid adaptation in patient care.
- A lack of established therapeutic guidelines and randomized clinical trials (RCTs) for COVID-19 treatment created treatment challenges.
Purpose of the Study:
- To describe the role of rheumatologists on the front lines of the COVID-19 pandemic.
- To explore the adaptation of rheumatological expertise and existing drug knowledge for novel coronavirus disease management.
- To report on the use of established arthritis and giant cell arteritis medications in treating COVID-19 patients.
Main Methods:
- Observational approach based on clinical experience and case series.
- Leveraging prior knowledge of anti-inflammatory and immunomodulatory drugs used in rheumatological conditions.
- Application of off-label drug use for COVID-19 treatment by frontline clinicians.
Main Results:
- Rheumatologists adapted their clinical activities and training to manage COVID-19 patients.
- Experience with drugs for arthritis and giant cell arteritis informed treatment decisions.
- Existing rheumatological medications were repurposed for COVID-19 treatment.
Conclusions:
- Rheumatologists played a crucial role in managing COVID-19 patients, particularly in the absence of specific therapies.
- Repurposing of established rheumatological drugs provided a therapeutic avenue for COVID-19.
- The pandemic underscored the adaptability of medical specialists in responding to global health crises.
Abstract:
SARS-CoV-2 infection has spread worldwide since it originated in December 2019, in Wuhan, China. The pandemic has largely demonstrated the resilience of the world's health systems and is the greatest health emergency since World War II. There is no single therapeutic approach to the treatment of COVID-19 and the associated immune disorder. The lack of randomised clinical trials (RCTs) has led different countries to tackle the disease based on case series, or from results of observational studies with off-label drugs. We as rheumatologists in general, and specifically rheumatology fellows, have been on the front line of the pandemic, modifying our activities and altering our training itinerary. We have attended patients, we have learned about the management of the disease and from our previous experience with drugs for arthritis and giant cell arteritis, we have used these drugs to treat COVID-19.
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