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Updated: Dec 17, 2025

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
[Two cases of rectal neuroendocrine carcinoma associated with long-standing ulcerative colitis]
Hazuki Miyazaki1, Tsunekazu Mizushima1, Norikatsu Miyoshi1
1Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University.
Abstract:
Two cases of neuroendocrine carcinoma, complicated with ulcerative colitis, were examined. Case 1:The patient developed ulcerative colitis at the age of 38, surgery was performed after a diagnosis of rectal cancer at the age of 53, and the patient was diagnosed with neuroendocrine carcinoma by pathological examination after resection. Post-surgery, metastatic nodules were detected in the liver and lungs. The patient is undergoing chemotherapy at this time. Case 2:The patient developed ulcerative colitis at the age of 59;at 72, a sigmoid colon tumor, in addition to multiple liver tumors, was detected. The patient was diagnosed with neuroendocrine carcinoma following biopsy. Chemotherapy was initiated;however, the patient died of cancer 12 months later.
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