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Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition
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Current understanding of adult neurogenesis in the mammalian brain: how does adult neurogenesis decrease with age?

Yoshitaka Kase1,2, Takuya Shimazaki1, Hideyuki Okano1

  • 1Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582 Japan.

Inflammation and Regeneration
|June 23, 2020
PubMed
Summary

Aging reduces the number of neural stem cells (NSCs) and neurogenesis. Mobilizing endogenous NSCs offers a promising regenerative medicine approach for brain injuries, overcoming challenges of cell transplantation.

Keywords:
Adult neurogenesisAgingNeural stem cellSubgranular zoneTransit amplifying progenitor cellVentricular-subventricular zone

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