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Updated: Dec 17, 2025

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
Invasive Aspergillosis Masquerading as Multiple Pulmonary Nodules: A Challenging Diagnosis
Mamta Chhabria1, Sharini Venugopal1, Venkata Satish Pendela1
1Internal Medicine, Rochester General Hospital, Rochester, USA.
Abstract:
Invasive pulmonary aspergillosis (IPA) is an aggressive fungal infection of the lungs characterized by tissue invasion by fungal hyphal elements. The definitive diagnosis is challenging because it relies on histopathological demonstration of fungal elements, and these days clinicians are relying more on bronchoalveolar lavage (BAL) cultures and serum biomarkers (galactomannan and beta-D-glucan). We would like to emphasize through our case the necessity to keep a high index of suspicion for IPA despite negative cultures and serum biomarkers in immunosuppressed patients and consider surgical biopsy early.
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