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Updated: Dec 17, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Acute disseminated encephalomyelitis after dengue.

Abdoulahy Diallo¹, Yacouba Dembele², Céline Michaud¹

¹Service De Médecine Polyvalente, Centre Hospitalier De Mayotte, Mamoudzou, Mayotte, France.

|June 23, 2020

Summary

Acute disseminated encephalomyelitis (ADEM) is a rare neurological complication following dengue infection. This case report details a 39-year-old woman diagnosed with ADEM after dengue fever.

Keywords:

ADEM, Acute Disseminated Encephalomyelitis Acute disseminated encephalomyelitis CSF, Cerebrospinal Fluid Dengue infection EEG, Electroencephalography MRI, Magnetic Resonance Imaging Mayotte PCR, Polymerase Chain Reaction

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Last Updated: Dec 17, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

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Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

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Published on: July 4, 2007

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum

Published on: April 10, 2018

Area of Science:

Neurology
Infectious Diseases
Public Health

Background:

Dengue fever, a vector-borne disease transmitted by Aedes aegypti mosquitoes, is a growing global health concern.
Neurological complications of dengue are uncommon, with acute disseminated encephalomyelitis (ADEM) being particularly rare.

Observation:

This report presents a case of ADEM occurring as a neurological complication in a 39-year-old woman during a dengue epidemic.
The diagnosis was supported by clinical presentation, characteristic MRI brain lesions, and serological evidence of dengue infection.

Findings:

The case highlights the potential for rare neurological sequelae following dengue virus infection.
ADEM diagnosis in this context relies on a combination of clinical, radiological, and serological findings.

Implications:

This case contributes to the limited literature on dengue-associated ADEM, emphasizing the need for heightened clinical suspicion.
Understanding these rare neurological manifestations is crucial for comprehensive patient management and public health preparedness in endemic regions.