Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Machine-intelligent multimodal algebot for intracavitary chemotherapy.

Nature nanotechnology·2026
Same author

In vivo dynamic hotspot-enhanced Raman spectroscopy via reconfigurable swarming nanoprobes.

Nature communications·2026
Same author

Deep Learning Assisted Motion Behavior Analysis of Catalytic Micromotors Based on Trajectory and Optical Flow.

Nano letters·2026
Same author

Triple-Level Information Encryption Enabled by Fluorescent Microspheres: Harnessing Structural Color, Fluorescence, and Purcell-Effect Spectral Key.

ACS applied materials & interfaces·2026
Same author

Gear-like MOF microrobots for single cell mechanotransduction of microvilli.

Nature communications·2026
Same author

Modular magnetic microrobot system for robust endoluminal navigation and high-radial force stent delivery in complex ductal anatomy.

Science advances·2025

Related Experiment Video

Updated: Dec 17, 2025

Remote Magnetic Actuation of Micrometric Probes for in situ 3D Mapping of Bacterial Biofilm Physical Properties
14:42

Remote Magnetic Actuation of Micrometric Probes for in situ 3D Mapping of Bacterial Biofilm Physical Properties

Published on: May 2, 2014

9.5K

Magnetic Nanomotor-Based Maneuverable SERS Probe.

Yong Wang1,2, Yuhuan Liu1,2, Yang Li3

  • 1Flexible Printed Electronic Technology Center and School of Materials Science and Engineering, Harbin Institute of Technology (Shenzhen), Shenzhen 518055, China.

Research (Washington, D.C.)
|June 23, 2020
PubMed
Summary
This summary is machine-generated.

This study introduces magnetic nanomotor-based SERS probes (MNM-SPs) for precise biochemical analysis. These controllable probes offer enhanced sensitivity and self-cleaning capabilities for targeted sensing applications.

More Related Videos

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements
08:50

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

2.6K
Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains
07:42

Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains

Published on: July 20, 2022

3.1K

Related Experiment Videos

Last Updated: Dec 17, 2025

Remote Magnetic Actuation of Micrometric Probes for in situ 3D Mapping of Bacterial Biofilm Physical Properties
14:42

Remote Magnetic Actuation of Micrometric Probes for in situ 3D Mapping of Bacterial Biofilm Physical Properties

Published on: May 2, 2014

9.5K
High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements
08:50

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

2.6K
Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains
07:42

Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains

Published on: July 20, 2022

3.1K

Area of Science:

  • Nanotechnology
  • Spectroscopy
  • Biomedical Engineering

Background:

  • Surface-enhanced Raman spectroscopy (SERS) offers ultrasensitive detection but conventional probes lack control and adaptability.
  • Passive SERS nanoparticles are widely used but limited in precise, targeted sensing at micro/nanoscales.

Purpose of the Study:

  • To develop a controllable and adaptable SERS probe by integrating micro/nanomotor technology with SERS sensing.
  • To demonstrate the maneuverability, enhanced mixing, self-cleaning, and cellular targeting capabilities of the novel probe.

Main Methods:

  • Fabrication of rod-like magnetic nanomotor-based SERS probes (MNM-SPs) using silica-coated magnetic nanoparticles decorated with silver nanoparticles (AgNPs).
  • Navigation and manipulation of MNM-SPs using external gradient magnetic fields for targeted delivery and obstacle avoidance.
  • Utilizing rotating magnetic fields to induce active rotation for efficient fluid stirring, analyte contact, and enhanced SERS signal acquisition.

Main Results:

  • MNM-SPs demonstrated on-demand navigation and precise targeting of sensing sites, including single cells.
  • Active rotation by MNM-SPs significantly improved analyte contact and SERS signal-to-noise ratio through efficient intracellular mixing.
  • The probes exhibited self-cleaning capabilities, addressing contamination issues common with traditional SERS probes.

Conclusions:

  • Magnetically activated MNM-SPs provide a controllable and adaptable platform for SERS sensing at the micro/nanoscale.
  • The developed probes show promise for advanced biochemical analysis, cellular imaging, and targeted diagnostics.
  • This work paves the way for smart, maneuverable sensing probes with enhanced performance and reusability.