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[Creatinin as predictor value of mortality in patients with acute coronary syndrome]
Anel Gómez-García1, Jorge Cruz-Balandrán, Alejandro Villatoro-Martínez
1Instituto Mexicano del Seguro Social, Centro de Investigación Biomédica de Michoacán, División de Investigación Clínica. Morelia, Michoacán, México.
Insights
Serum creatinine (Cr) levels upon admission for Acute Coronary Syndrome (ACS) predict patient mortality. This easily accessible marker in the emergency department aids in assessing prognosis for ACS patients.
Area of Science:
- Cardiology
- Clinical Biochemistry
Context:
- Cardiovascular diseases are the leading global cause of death.
- Acute Coronary Syndrome (ACS) is a critical condition requiring prompt risk assessment.
- Emergency departments (ED) are primary points of care for ACS patients.
Purpose:
- To evaluate serum creatinine (Cr) as a prognostic indicator for mortality in Acute Coronary Syndrome (ACS) patients admitted to the ED shock room.
- To determine the association between admission serum Cr levels and patient outcomes (mortality).
Summary:
- A prospective study of 95 ACS patients (NSTE-ACS and STEMI) admitted to the ED shock room.
- Serum creatinine (Cr) levels, cardiovascular risk factors, and patient disposition were analyzed.
- Significantly different Cr levels were observed between patients who survived and those who died (p = 0.0001).
Impact:
- Admission serum creatinine (Cr) offers valuable prognostic information for mortality in ACS patients.
- Cr serves as an accessible and readily available prognostic marker within the ED setting.
- This finding can aid clinicians in risk stratification and management decisions for ACS patients.
Background:
Cardiovascular diseases have become the leading cause of death worldwide.
Objective:
To estimate serum creatinine (Cr) as a prognostic value of mortality in patients with Acute Coronary Syndrome (ACS), which was admitted to the shock room in the emergency department (ED).
Material And Methods:
A transversal, prospective study, which included 95 patients with ACS who were admitted to the shock room. The following variables were studied: laboratory tests with Cr, cardiovascular risk factors (CVRF), days of hospital stay, service to which it was derived and discharge condition (alive or dead). Statistical analysis was through SPSS v. 23.
Results:
The diagnosis of admission was ACS without ST elevation (NSTE-ACS), 72.6%; and Acute Myocardial Infarction with ST elevation (STEMI), 27.4%. The 63.2% were discharged alive, 13.7% transferred to a third level hospital and 23.2% died. There was a difference in the level of Cr between living and deceased (p = 0.0001).
Conclusions:
CR on admission of the patient with SCA provides prognostic information for mortality, and can be established as a prognostic marker of easy access and available in the ED.
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