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Related Concept Videos

Accessory Structures of the Skin: Sweat Glands01:20

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Sweat glands or sudoriferous glands are one of the important accessory structures of the skin. They are small, coiled tubular structures located in the dermis, the middle layer of the skin. Sweat glands are responsible for producing and secreting sweat, a watery fluid that helps regulate body temperature and excrete waste products.
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Exocrine glands are those that release their secretions through ducts. Based on their mode of secretion, they can be classified into merocrine, apocrine, and holocrine.
Merocrine Secretion
Merocrine secretion is the most common type of exocrine secretion. The secretions are enclosed in vesicles and moved to the cell's apical surface, where the contents are released by exocytosis. For example, mucous, a watery secretion rich in the glycoprotein mucin, is a merocrine secretion. The eccrine...
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Accessory Structures of the Skin: Sebaceous Glands01:21

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A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
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Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...
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Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
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Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
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Updated: Dec 17, 2025

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
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Apocrine Chromhidrosis.

Aadarsh Shah1, Zoi Tsianou2, Ravi Suchak2

  • 1St John's Institute of Dermatology, Guy's and St Thomas' Hospital, Great Maze Pond, London, United Kingdom; and.

The American Journal of Dermatopathology
|June 23, 2020
PubMed
Summary
This summary is machine-generated.

Apocrine chromhidrosis, a rare condition causing colored sweat, was diagnosed in a woman with unusual pink sweating. Histology confirmed lipofuscin granules in apocrine glands, highlighting a unique case presentation.

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Area of Science:

  • Dermatology
  • Histopathology

Background:

  • Apocrine chromhidrosis is a rare condition characterized by the secretion of colored sweat from apocrine glands.
  • These glands are found in specific body areas, including the axillae, anogenital region, areolae, trunk, face, and scalp.

Observation:

  • A 65-year-old woman presented with sudden-onset pink sweating, primarily affecting her axillae and pelvis.
  • The condition caused noticeable staining of clothing and bed sheets.

Findings:

  • Physical examination revealed no significant abnormalities.
  • Histology with immunostaining identified focally prominent yellow-brown lipofuscin granules within the apocrine secretory cells, confirming the diagnosis.
  • The pink/red coloration and inguinal canal involvement are atypical presentations of apocrine chromhidrosis.

Implications:

  • Apocrine chromhidrosis can lead to significant psychosocial distress for affected individuals.
  • Effective treatment strategies for this rare condition remain a challenge.
  • This case expands the understanding of clinical variations and diagnostic markers in apocrine chromhidrosis.