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Updated: Dec 17, 2025

A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
SPHN/PHRT: Forming a Swiss-Wide Infrastructure for Data-Driven Sepsis Research
Adrian Egli1,2, Manuel Battegay3, Andrea C Büchler3
1Clinical Bacteriology and Mycology, University Hospital Basel, Basel, Switzerland.
Abstract:
Sepsis is a highly heterogenous syndrome with variable causes and outcomes. As part of the SPHN/PHRT funding program, we aim to build a highly interoperable, interconnected network for data collection, exchange and analysis of patients on intensive care units in order to predict sepsis onset and mortality earlier. All five University Hospitals, Universities, the Swiss Institute of Bioinformatics and ETH Zurich are involved in this multi-disciplinary project. With two prospective clinical observational studies, we test our infrastructure setup and improve the framework gradually and generate relevant data for research.

