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Related Concept Videos

Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

1.0K
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.0K
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
604
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
592
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

211
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
211
Lipid Absorption01:24

Lipid Absorption

2.3K
Dietary triglycerides from chyme in the duodenum are mixed with bile salts produced by the liver to emulsify fats. As a result, large droplets are broken down into smaller ones, increasing the surface area for enzymatic action. Once emulsified, pancreatic lipases hydrolyze the triglycerides into free fatty acids and monoglycerides.
These breakdown products bind with bile salts and lecithin to form micelles, which quickly pass between microvilli to come in close contact with the apical...
2.3K
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

1.0K
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.0K

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Related Experiment Video

Updated: Dec 17, 2025

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
06:35

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

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Hypertriglyceridemia and acute pancreatitis.

Allison L Yang1, Julia McNabb-Baltar2

  • 1Division of Gastroenterology & Hepatology, Weill Cornell Medical College, New York, NY, USA.

Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [Et Al.]
|June 24, 2020
PubMed
Summary

High triglycerides (hypertriglyceridemia) are a common cause of acute pancreatitis, often leading to severe illness. Prompt recognition and management of hypertriglyceridemia are crucial for preventing recurrent pancreatitis.

Keywords:
Acute pancreatitisHypertriglyceridemiaTriglycerides

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Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
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Last Updated: Dec 17, 2025

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Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
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Area of Science:

  • Endocrinology
  • Gastroenterology
  • Metabolic Disorders

Background:

  • Hypertriglyceridemia is the third leading cause of acute pancreatitis.
  • It often co-occurs with metabolic disorders, diabetes, alcohol abuse, or certain medications.

Purpose of the Study:

  • To review the etiology, pathogenesis, and clinical course of acute pancreatitis induced by hypertriglyceridemia.
  • To emphasize the importance of recognizing and managing hypertriglyceridemia in acute pancreatitis.

Main Methods:

  • Literature review focusing on hypertriglyceridemia-induced acute pancreatitis.
  • Analysis of clinical presentations, disease severity, and treatment strategies.

Main Results:

  • Hypertriglyceridemia-induced pancreatitis can present similarly to other causes but often leads to more severe disease and organ failure.
  • Standard acute pancreatitis care includes fluid resuscitation, pain control, and nutritional support.
  • Specific treatments for hypertriglyceridemia include apheresis or insulin therapy.

Conclusions:

  • Early identification of hypertriglyceridemia is vital for effective initial and long-term management of acute pancreatitis.
  • Managing hypertriglyceridemia is essential for preventing recurrent episodes of acute pancreatitis.