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Assignment of the T-cell differentiation gene MAL to human chromosome 2, region cen----q13
M A Alonso1, D E Barton, U Francke
1Department of Human Genetics, Yale University School of Medicine, New Haven, CT 06510.
Immunogenetics
|January 1, 1988
Abstract:
A cDNA clone has recently been isolated that encodes a protein expressed only in the intermediate and late stages of T-cell differentiation, termed MAL. The polypeptide deduced from the MAL cDNA sequence contains four potential transmembrane domains. We have used a panel of 28 human X rodent hybrid cell lines to assign the MAL gene to the proximal long arm of human chromosome 2, region cen----q13. The significance of the MAL map position and its relationship with other genes on chromosome 2 are discussed.