Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

9.7K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
9.7K
Introduction to Mechanisms of Enzyme Catalysis01:13

Introduction to Mechanisms of Enzyme Catalysis

10.2K
For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes...
10.2K
Multi-Step Reactions02:31

Multi-Step Reactions

8.4K
Chemical reactions often occur in a stepwise fashion involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs. Each of the steps in a reaction mechanism is called an elementary reaction. These...
8.4K
Reaction Mechanisms03:06

Reaction Mechanisms

30.2K
Chemical reactions often occur in a stepwise fashion, involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs.
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
30.2K
Mechanical Protein Functions01:58

Mechanical Protein Functions

5.4K
Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force. 
5.4K
Catalysis02:50

Catalysis

29.8K
The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
29.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mehanokemija v Evropi: od kod prihajamo in kje smo danes.

Acta chimica Slovenica·2026
Same author

What can a kinetic modelling approach reveal about the intricacies of mechanochemical kinetics?

Physical chemistry chemical physics : PCCP·2026
Same author

Mechanochemical Amidation Mediated by 1,1'-Oxalyldiimidazole for the Synthesis of Agrochemicals.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same author

Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations.

Angewandte Chemie (International ed. in English)·2026
Same author

Mechanochemical Methods for Amide Bond Formation.

Chemical reviews·2026
Same author

Scaling up mechanochemical reactions: linking crystalline phase evolution studied <i>via in situ</i> PXRD with kinetics from MCR-ALS.

Chemical science·2026

Related Experiment Video

Updated: Dec 17, 2025

Reliable Mechanochemistry: Protocols for Reproducible Outcomes of Neat and Liquid Assisted Ball-mill Grinding Experiments
13:05

Reliable Mechanochemistry: Protocols for Reproducible Outcomes of Neat and Liquid Assisted Ball-mill Grinding Experiments

Published on: January 23, 2018

11.1K

Kinetics of mechanochemical transformations.

Maria Carta1, Evelina Colacino2, Francesco Delogu1

  • 1Department of Mechanical, Chemical and Materials Engineering, University of Cagliari, via Marengo 2, 09123 Cagliari, Italy. francesco.delogu@unica.it.

Physical Chemistry Chemical Physics : PCCP
|June 24, 2020
PubMed
Summary

Mechanochemistry uses mechanical force for chemical reactions, enabling solventless synthesis and unique materials. This study introduces a kinetic model to understand and control these processes at micro and macro scales.

More Related Videos

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
09:42

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Published on: January 16, 2016

9.3K
Demonstrating the Simplicity and In Situ Temperature Monitoring of the Mechanochemical Synthesis of Metal Chalcogenides Suitable for Thermoelectrics
04:09

Demonstrating the Simplicity and In Situ Temperature Monitoring of the Mechanochemical Synthesis of Metal Chalcogenides Suitable for Thermoelectrics

Published on: August 30, 2024

678

Related Experiment Videos

Last Updated: Dec 17, 2025

Reliable Mechanochemistry: Protocols for Reproducible Outcomes of Neat and Liquid Assisted Ball-mill Grinding Experiments
13:05

Reliable Mechanochemistry: Protocols for Reproducible Outcomes of Neat and Liquid Assisted Ball-mill Grinding Experiments

Published on: January 23, 2018

11.1K
Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
09:42

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Published on: January 16, 2016

9.3K
Demonstrating the Simplicity and In Situ Temperature Monitoring of the Mechanochemical Synthesis of Metal Chalcogenides Suitable for Thermoelectrics
04:09

Demonstrating the Simplicity and In Situ Temperature Monitoring of the Mechanochemical Synthesis of Metal Chalcogenides Suitable for Thermoelectrics

Published on: August 30, 2024

678

Area of Science:

  • Materials Science
  • Chemical Engineering
  • Solid-State Chemistry

Background:

  • Mechanochemistry is a rapidly growing field with applications in materials science, chemical synthesis, and pharmaceuticals.
  • It offers solventless processes and access to unique materials not achievable through traditional methods.
  • Understanding the underlying mechanisms is crucial for developing reliable mechanochemical technologies.

Purpose of the Study:

  • To develop a kinetic model that bridges macroscopic observations with microscopic events in mechanochemical transformations.
  • To account for the statistical nature of mechanical powder processing.
  • To provide a framework for understanding and controlling mechanochemical reactions.

Main Methods:

  • Development of a novel kinetic model.
  • Application of the model to specific case studies.
  • Derivation of kinetic equations for experimental data fitting.

Main Results:

  • The proposed kinetic model successfully relates macroscopic and microscopic scales.
  • The model accounts for the statistical nature of powder processing.
  • Kinetic equations derived from the model provide insights into microscopic activation features.

Conclusions:

  • The developed kinetic model offers a powerful tool for understanding mechanochemical processes.
  • It enables better control over mechanochemical transformations.
  • This work facilitates the advancement of mechanochemistry in various scientific and industrial applications.