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Discovering small-molecule therapeutics against SARS-CoV-2

Vaibhav Tiwari1, Jacob C Beer2, Nehru Viji Sankaranarayanan3

  • 1Department of Microbiology and Immunology, College of Graduate Studies, Midwestern University Downers Grove, IL 6051, USA; Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, IL 60515, USA.

Drug Discovery Today
|June 24, 2020
PubMed
Summary

This review explores novel therapeutic targets for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), beyond traditional protease inhibitors. It highlights unexplored strategies like disrupting viral protein oligomerization and host-virus interactions to combat COVID-19.

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