[Understanding and prevention of D-dimer elevation in coronavirus disease 2019 in traditional Chinese medicine]

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Qianfei Wang1, Chenxi Wang2, Jianqiang Mei3

  • 1Graduate School, Hebei College of Traditional Chinese Medicine, Shijiazhuang 050091, Hebei, China.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
|June 25, 2020
PubMed

Insights

Elevated D-dimer levels in patients with coronavirus disease 2019 (COVID-19) correlate with illness severity. Traditional Chinese Medicine (TCM) offers insights into managing blood stasis and improving circulation for COVID-19 patients.

Area of Science:

  • Internal Medicine
  • Pathology
  • Traditional Chinese Medicine

Background:

  • The 2019 Novel Coronavirus (2019-nCoV) pandemic necessitates understanding its impact on blood coagulation.
  • Elevated D-dimer levels in coronavirus disease 2019 (COVID-19) patients are linked to increased illness severity.

Purpose of the Study:

  • To review the mechanism and clinical significance of D-dimer elevation in COVID-19.
  • To explore the Traditional Chinese Medicine (TCM) perspective on blood stasis in COVID-19.
  • To outline TCM methods for promoting blood circulation and removing stasis in COVID-19 patients.

Main Methods:

  • Literature review of D-dimer levels in COVID-19 patients.
  • Analysis of Western medicine's understanding of hypercoagulable states.
  • Examination of TCM theories and therapeutic approaches for blood stasis.

Main Results:

  • D-dimer elevation in COVID-19 indicates hypercoagulability and correlates with disease severity.
  • TCM identifies these conditions as "blood stasis" (Xue Yu).
  • TCM therapies aim to improve microcirculation and resolve blood stasis.

Conclusions:

  • Understanding the link between D-dimer, hypercoagulability, and "blood stasis" is crucial for COVID-19 management.
  • TCM offers valuable strategies for addressing impaired blood coagulation in COVID-19.
  • Further research into TCM's role in preventing and treating COVID-19-related coagulation disorders is warranted.

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