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Updated: Dec 17, 2025

Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model
Published on: November 4, 2022
A rare case of penile metastases from small cell prostate cancer
Pablo Garrido-Abad1, Miguel Ángel Rodríguez-Cabello1, Roberto Vera-Berón2
1Urology Department, Hospital Universitario Sanitas La Moraleja, Universidad Francisco de Vitoria, Madrid, Spain.
Abstract:
We present a case of an 83-year-old-male with painless penile nodules several months after he was diagnosed with pure prostatic small cell carcinoma. Penile doppler ultrasound and magnetic resonance imaging demonstrated solid nodules in both corpora cavernosa. Fine-needle aspiration of the nodules with immunohistochemical examination confirmed prostatic small cell carcinoma origin of metastases. Small cell carcinoma of the prostate is a rare disorder accounting for less than 1% of all prostate cancers, the penis being an uncommon site for metastasis. An extremely low number of cases of penile metastases from prostatic small cell carcinoma has been reported to date in the literature.

