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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Gastric Ewing Sarcoma identified on a Meckel's scan.

Lavi Nissim1, Gerald Mandell1

  • 1Department of Radiology, Phoenix Children's Hospital, 1919 E Thomas Rd. Phoenix, AZ 85016 USA.

Radiology Case Reports
|June 25, 2020
PubMed
Summary

Ewing Sarcoma, a rare pediatric cancer, can occur in the stomach. This case highlights its unusual presentation as a stomach defect detected via scintigraphy.

Keywords:
Ewing SarcomaMeckel's scanPNETPrimitive Neuroectodermal tumor

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Area of Science:

  • Oncology
  • Pediatric Oncology
  • Skeletal and Soft Tissue Tumors

Background:

  • Ewing Sarcoma is a rare bone and soft tissue cancer, primarily affecting children and adolescents.
  • It is the second most common pediatric malignancy and primary bone tumor.
  • A characteristic translocation, t(11;22), is present in most Ewing Sarcoma cases.

Observation:

  • Extraskeletal Ewing Sarcoma of the stomach is exceptionally rare.
  • This case involved a patient presenting with gastrointestinal bleeding.
  • A filling defect in the stomach was initially detected using technetium-99m pertechnetate scintigraphy.

Findings:

  • The study reports a rare case of primary Ewing Sarcoma originating in the stomach.
  • The tumor was initially identified as a gastric filling defect during diagnostic imaging.
  • This highlights the potential for Ewing Sarcoma to manifest in extraskeletal sites.

Implications:

  • This case expands the known spectrum of Ewing Sarcoma presentation.
  • It underscores the importance of considering rare diagnoses in challenging clinical scenarios.
  • Accurate and timely diagnosis is crucial for appropriate patient management and treatment of Ewing Sarcoma.