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COVID-19 and Heart: From Clinical Features to Pharmacological Implications

Vincenzo Russo1, Roberta Bottino1, Andreina Carbone1

  • 1Division of Cardiology, Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", Monaldi Hospital, 80131 Naples, Italy.

Journal of Clinical Medicine
|June 26, 2020
PubMed

Insights

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) impacts cardiovascular disease (CVD) patients significantly. This review details COVID-19

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • The global COVID-19 pandemic, caused by SARS-CoV-2, presents significant challenges.
  • Emerging data suggest a strong link between cardiovascular diseases (CVD) and COVID-19 patient outcomes.
  • Understanding this association is crucial for managing the pandemic's impact.

Purpose of the Study:

  • To review the cardiac manifestations of COVID-19 at hospital admission.
  • To analyze the acute cardiac presentations in COVID-19 patients.
  • To evaluate the clinical outcomes for patients with pre-existing CVD and discuss pharmacological management.

Main Methods:

  • Systematic literature review of studies on COVID-19 and cardiovascular disease.
  • Analysis of epidemiological data and clinical features at admission.
  • Examination of acute cardiac events and patient prognosis.

Main Results:

  • COVID-19 patients with underlying CVD exhibit distinct clinical features and poorer prognosis.
  • Acute cardiac injury and arrhythmias are common presentations.
  • Specific pharmacological considerations are highlighted for managing these patients.

Conclusions:

  • SARS-CoV-2 infection poses a substantial risk to individuals with cardiovascular disease.
  • Prompt recognition of cardiac involvement and tailored management strategies are essential.
  • Further research is needed to optimize treatment protocols for COVID-19 patients with CVD.

Keywords:
angiotensin-converting enzyme inhibitorarrhythmiascardiac biomarkerscardiovascular diseasescoronavirus disease 2019 (COVID-19)myocardial injury

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