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[Iodine-induced thyroid dysfunction]
F Eilsberger1, M Luster2, J Feldkamp3
1Klinik für Nuklearmedizin, Universitätsklinikum Marburg, Baldingerstraße, 35043, Marburg, Deutschland. friederike.mueller@staff.uni-marburg.de.
Medizinische Klinik, Intensivmedizin Und Notfallmedizin
|June 26, 2020
Summary
Iodine-induced thyroid dysfunction, though rare, requires prompt recognition. Treatment for iodine-induced hyperthyroidism involves antithyroid drugs and perchlorate, with prophylaxis recommended for high-risk individuals.
Area of Science:
- Endocrinology
- Thyroidology
Background:
- Iodine-induced thyroid dysfunction, while uncommon, presents significant clinical challenges.
- Key triggers include iodine-containing contrast agents, amiodarone, and disinfectants.
- Distinguishing between hypothyroidism and hyperthyroidism is crucial, as hypothyroidism is typically self-limiting.
Purpose of the Study:
- To review current knowledge on the pathogenesis of iodine-induced thyroid dysfunction.
- To outline therapeutic strategies for managing iodine-induced thyroid dysfunction.
- To discuss methods for preventing iodine-induced thyroid dysfunction.
Main Methods:
- A comprehensive literature search of recent publications was conducted.
- Findings were integrated with practical clinical experience.
Main Results:
- Iodine-induced hyperthyroidism management focuses on reducing thyroid hormone synthesis and iodine uptake.
- Antithyroid drugs and perchlorate are primary therapeutic agents for hyperthyroidism.
- Prophylaxis for contrast agent-induced hyperthyroidism may involve perchlorate and antithyroid drugs.
Conclusions:
- Prompt diagnosis and management of iodine-induced thyroid dysfunction are essential.
- Therapeutic strategies aim to mitigate thyroid hormone overproduction and iodine accumulation.
- Prophylactic measures are vital for high-risk patients undergoing procedures involving iodine exposure.
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