Related Experiment Video
Updated: Dec 17, 2025

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique
Published on: May 23, 2021
Outcome of surgery for chronic suppurative otitis media with resistant Pseudomonas aeruginosa
1Department of Otolaryngology, Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, 6 Weizmann Street, 6423906, Tel-Aviv, Israel. orencavel@gmail.com.
Objective:
To assess the effectiveness of surgical treatment of active chronic suppurative otitis media (CSOM) with ciprofloxacin-resistant Pseudomonas aeruginosa (P. aeruginosa) that failed comprehensive local and systemic treatment.
Study Design:
Retrospective case review.
Setting:
Tertiary referral center.
Patients:
Eleven patients with ciprofloxacin-resistant P. aeruginosa CSOM that remained active despite comprehensive local and systemic treatment. All patients were operated by a single surgeon between February 2016 and July 2019 INTERVENTION(S): Tympanoplasty alone was performed in seven cases and accompanied by mastoidectomy in the other four cases.
Main Outcome Measure(S):
Resolution of infection and tympanic graft take on otoscopy. The secondary outcome measure is hearing.
Results:
Tympanic graft take was successful and the infectious process was resolved in 8 out of the 11 cases, yielding a success rate of 73%. The average follow-up was 20 months. No surgical complications occurred.
Conclusions:
Tympanoplasty, with or without mastoidectomy, is safe and yields acceptable anatomical and functional success rates when intensive local and systemic treatment fails to stop the purulent discharge.
Insights
Surgical treatment, including tympanoplasty with or without mastoidectomy, effectively resolves chronic suppurative otitis media (CSOM) caused by ciprofloxacin-resistant Pseudomonas aeruginosa when other treatments fail.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Surgical Innovation
Background:
- Chronic suppurative otitis media (CSOM) poses a significant challenge, particularly when caused by antibiotic-resistant pathogens.
- Pseudomonas aeruginosa resistant to ciprofloxacin complicates treatment, often necessitating advanced interventions.
Purpose of the Study:
- To evaluate the efficacy of surgical interventions for CSOM caused by ciprofloxacin-resistant Pseudomonas aeruginosa.
- To assess surgical outcomes in patients who failed prior local and systemic therapies.
Main Methods:
- Retrospective case review of eleven patients treated at a tertiary referral center.
- Surgical interventions included tympanoplasty alone or with mastoidectomy.
- Outcomes assessed by infection resolution and tympanic graft take, with hearing as a secondary measure.
Main Results:
- A 73% success rate was achieved, with 8 out of 11 patients showing resolution of infection and successful tympanic graft take.
- The average follow-up period was 20 months.
- No surgical complications were reported.
Conclusions:
- Tympanoplasty, with or without mastoidectomy, offers a safe and effective treatment option for refractory CSOM.
- Surgery provides acceptable anatomical and functional success rates when conservative treatments are insufficient.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Tonsillitis II: Management
Suctioning the Nasopharyngeal Airway
Equipment Required
Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Pneumothorax-II
Clinical Manifestations:

