Outcome of surgery for chronic suppurative otitis media with resistant Pseudomonas aeruginosa

O Cavel1, O J Ungar2, Y Oron2

  • 1Department of Otolaryngology, Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, 6 Weizmann Street, 6423906, Tel-Aviv, Israel. orencavel@gmail.com.

Abstract

Insights

Surgical treatment, including tympanoplasty with or without mastoidectomy, effectively resolves chronic suppurative otitis media (CSOM) caused by ciprofloxacin-resistant Pseudomonas aeruginosa when other treatments fail.

Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Surgical Innovation

Background:

  • Chronic suppurative otitis media (CSOM) poses a significant challenge, particularly when caused by antibiotic-resistant pathogens.
  • Pseudomonas aeruginosa resistant to ciprofloxacin complicates treatment, often necessitating advanced interventions.

Purpose of the Study:

  • To evaluate the efficacy of surgical interventions for CSOM caused by ciprofloxacin-resistant Pseudomonas aeruginosa.
  • To assess surgical outcomes in patients who failed prior local and systemic therapies.

Main Methods:

  • Retrospective case review of eleven patients treated at a tertiary referral center.
  • Surgical interventions included tympanoplasty alone or with mastoidectomy.
  • Outcomes assessed by infection resolution and tympanic graft take, with hearing as a secondary measure.

Main Results:

  • A 73% success rate was achieved, with 8 out of 11 patients showing resolution of infection and successful tympanic graft take.
  • The average follow-up period was 20 months.
  • No surgical complications were reported.

Conclusions:

  • Tympanoplasty, with or without mastoidectomy, offers a safe and effective treatment option for refractory CSOM.
  • Surgery provides acceptable anatomical and functional success rates when conservative treatments are insufficient.

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