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Fluorescence-Based Measurements of Phosphatidylserine/Phosphatidylinositol 4-Phosphate Exchange Between Membranes
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Phosphoinositide-specific phospholipase C isoforms are conveyed by osteosarcoma-derived extracellular vesicles

Enrica Urciuoli1, Martina Leopizzi2, Valeria Di Maio2

  • 1Multifactorial Disease and Complex Phenotype Research Area, Research Centre, Bambino Gesù Children's Hospital, Rome, Italy.

Journal of Cell Communication and Signaling
|June 26, 2020
PubMed
Summary

Osteosarcoma cancer cells release extracellular vesicles containing phosphoinositide-specific phospholipase C (PI-PLC) enzymes. These vesicles may serve as biomarkers for monitoring osteosarcoma progression.

Keywords:
Confocal microscopeExtracellular vesiclesFACS analysisOsteosarcomaPI-PLC

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