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Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
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Slow on the Uptake, Progression to Heartbreak.
Ashley K Binder1, John P Haydek1, Siddhant Parihar1
1Emory University, Atlanta, GA, USA.
Summary
Serotonin syndrome, a dangerous condition from excess serotonin, is rising due to increased medication use. Prompt recognition and treatment are vital for patient survival and improved outcomes.
Area of Science:
- Clinical Medicine
- Pharmacology
- Toxicology
Background:
- Serotonin syndrome prevalence is increasing with wider use of serotonergic agents.
- It is a potentially fatal condition resulting from excessive serotonergic activity.
- Causes include prescription drugs, illicit substances, or combinations thereof.
Observation:
- A 25-year-old woman presented with confusion, rigidity, high fever, and reduced biventricular function.
- Her presentation was linked to polysubstance abuse, including cocaine.
- Echocardiogram revealed reduced biventricular function.
Findings:
- The patient was diagnosed with serotonin syndrome complicated by takotsubo cardiomyopathy.
- Diagnosis was based on substance use history, clinical symptoms, and echocardiogram results.
Implications:
- This case highlights the critical need for early recognition and management of serotonin syndrome.
- Prompt intervention can significantly improve patient morbidity and mortality.
- Awareness of serotonin syndrome is crucial for clinicians managing patients with substance abuse.
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