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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Non-Diazo C-H Insertion Approach to Cyclobutanones through Oxidative Gold Catalysis.

Zhitong Zheng1, Youliang Wang1,2, Xu Ma1

  • 1Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, 93106, USA.

Angewandte Chemie (International Ed. in English)
|June 26, 2020
PubMed
Summary

We developed an easy method for making cyclobutanones using gold carbenes. This approach simplifies the synthesis of these versatile compounds, offering new possibilities in organic chemistry.

Keywords:
C−H insertioncatalysiscyclobutanonegold carbeneoxidation

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