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Development of a Risk Score to Predict 90-Day Readmission After Coronary Artery Bypass Graft
Rodrigo Zea-Vera1, Qianzi Zhang1, Arsalan Amin1
1Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
Insights
A new risk score predicts 90-day readmission after coronary artery bypass grafting (CABG) surgery. This tool identifies high-risk patients, enabling targeted interventions to reduce hospital readmissions.
Area of Science:
- Cardiovascular Surgery
- Health Services Research
- Predictive Analytics
Background:
- Readmission after coronary artery bypass grafting (CABG) impacts quality metrics and hospital reimbursement.
- Developing a predictive model for 90-day readmission risk is crucial for patient care and hospital management.
Purpose of the Study:
- To develop and validate a risk score system for predicting 90-day readmission in patients undergoing CABG.
- To identify key demographic and clinical factors associated with increased readmission risk.
Main Methods:
- Utilized the National Readmission Database (2013-2014) with a weighted cohort of 234,483 CABG patients.
- Employed multivariable analysis on a training set (60%) to identify risk factors and developed a point-based risk score.
- Validated the model's performance using a test set (40%) with receiver operating characteristic analysis and accuracy assessment.
Main Results:
- The overall 90-day readmission rate after CABG was 19%.
- Nine demographic and clinical variables were identified as significant predictors.
- The final risk score ranged from 0 to 52, with length of stay >10 days and Medicaid insurance being major contributors.
- The model achieved a C-statistic of 0.67 and an accuracy of 77% at an optimal cutoff of 18 points.
Conclusions:
- Ninety-day readmission is a significant concern following CABG surgery.
- The developed risk score, based on 9 factors, accurately predicts readmission risk (77% accuracy).
- This risk score can guide the allocation of post-discharge resources to high-risk CABG patients, aiming to reduce readmissions.
Background:
Readmission after coronary artery bypass grafting (CABG) is used for quality metrics and may negatively affect hospital reimbursement. Our objective was to develop a risk score system from a national cohort that can predict 90-day readmission risk for CABG patients.
Methods:
Using the National Readmission Database between 2013 and 2014, we identified 104,930 patients discharged after CABG, for a total of 234,483 patients after weighted analysis. Using structured random sampling, patients were divided into a training set (60%) and test data set (40%). In the training data set, we used multivariable analysis to identify risk factors. A point system risk score was developed based on the odds ratios. Variables with odds ratio less than 1.3 were excluded from the final model to reduce noise. Performance was assessed in the test data set using receiver operator characteristics and accuracy.
Results:
In the United States, overall 90-day readmission rate after CABG was 19% (n = 44,559 of 234,483). Nine demographic and clinical variables were identified as important in the training data set. The final risk score ranged from 0 to 52; the 2 largest risks were associated with length of stay greater than 10 days (score = +10) and Medicaid insurance (score = +7). The final model's C-statistic was 0.67. Using an optimal cutoff of 18 points, the accuracy of the risk score was 77%.
Conclusions:
Ninety-day readmission after CABG surgery is frequent. A readmission risk score higher than 18 points predicts readmission in 77% of patients. Based on 9 demographic and clinical factors, this risk score can be used to target high-risk patients for additional postdischarge resources to reduce readmission.
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