Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Influence of cations on nitrate-to-ammonia synthesis over NiO:SnO<sub>2</sub>: insights from differential electrochemical mass spectrometry.

Chemical communications (Cambridge, England)·2026
Same author

Electrolytic Bubble Coalescence on Hydrophobic Cavity Arrays Determines Departure Radius and Lowers Electrolyte Supersaturation.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

Mechanochemistry for the Sustainable Synthesis of Organic Hole Transport Materials in Perovskite Solar Cells.

Crystal growth & design·2025
Same author

Additive manufacturing of hollow connected networks for solar photo-Fenton-like catalysis.

RSC sustainability·2024
Same author

Temperature promotes selectivity during electrochemical CO<sub>2</sub> reduction on NiO:SnO<sub>2</sub> nanofibers.

Journal of materials chemistry. A·2024
Same author

Characterizing Acoustic Behavior of Silicon Microchannels Separated by a Porous Wall.

Micromachines·2024
Same journal

Correction: Kang et al. Fluid Flow to Electricity: Capturing Flow-Induced Vibrations with Micro-Electromechanical-System-Based Piezoelectric Energy Harvester. <i>Micromachines</i> 2024, <i>15</i>, 581.

Micromachines·2026
Same journal

Femtosecond Laser Texturing of Wood Coatings with Bio-Based Epoxy and Wax Additives for Enhanced Hydrophobicity.

Micromachines·2026
Same journal

Engineering of Optoelectronic Devices for Renewable Energy Applications.

Micromachines·2026
Same journal

Phase Transformation and Electrochemical Behavior of Hexagonal TiO<sub>2</sub> Nanotubes Under Different Annealing Temperatures and Heating Rates.

Micromachines·2026
Same journal

Process Optimization and Predictive Modeling of Femtosecond Laser Precision Milling for Commercial PMMA Slices.

Micromachines·2026
Same journal

A Hybrid Preprocessing Multi-Objective Surrogate Model for Thermal MEMS Actuators.

Micromachines·2026
See all related articles

Related Experiment Video

Updated: Dec 17, 2025

A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules
10:45

A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules

Published on: June 20, 2020

10.7K

Microfluidic Droplet-Storage Array.

Hoon Suk Rho1,2, Han Gardeniers2

  • 1Department of Instructive Biomaterials Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands.

Micromachines
|June 27, 2020
PubMed
Summary
This summary is machine-generated.

This study demonstrates a microfluidic droplet-storage array for continuous operation, enabling precise control and flexible manipulation of water-in-oil droplets for complex chemical and biologic reactions.

Keywords:
droplet arraymicrofluidicsmicrovalve

More Related Videos

Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses
09:43

Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses

Published on: March 8, 2024

2.3K
Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

22.7K

Related Experiment Videos

Last Updated: Dec 17, 2025

A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules
10:45

A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules

Published on: June 20, 2020

10.7K
Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses
09:43

Author Spotlight: Unveiling the Polyfunctionality and Heterogeneity in Immune Responses

Published on: March 8, 2024

2.3K
Fluorescence detection methods for microfluidic droplet platforms
14:16

Fluorescence detection methods for microfluidic droplet platforms

Published on: December 10, 2011

22.7K

Area of Science:

  • Microfluidics
  • Biotechnology
  • Chemical Engineering

Background:

  • Microfluidic devices offer precise control over small fluid volumes.
  • Efficient droplet manipulation and storage are crucial for complex assays.
  • Existing platforms often lack continuous operation and flexible handling capabilities.

Purpose of the Study:

  • To demonstrate a microfluidic droplet-storage array with continuous operation capabilities.
  • To enable flexible manipulation, including storage, repositioning, retrieval, injection, and restoration of droplets.
  • To showcase the platform's potential for sequential dosing in droplet-based reactors.

Main Methods:

  • Fabrication of a microfluidic chip with four valve-assisted droplet generators and a 3x16 droplet-storage array.
  • Integration of pneumatically actuated microvalves for precise control of aqueous phase dispensing and carrier fluid flow.
  • Validation of droplet size under various operating conditions (pressures, dispensing time).
  • Demonstration of flexible droplet addressing, storage, and rearrangement within the array.
  • Performance of serial injections into retrieved droplets for sequential dosing.

Main Results:

  • Continuous operation of droplet formation, storage, repositioning, retrieval, injection, and restoration was achieved.
  • Precise control over water-in-oil droplet manipulation was enabled by microvalves.
  • Droplet size was validated across different operating parameters.
  • Flexible droplet addressing and rearrangement within the storage array were successfully demonstrated.
  • Sequential dosing into incubated droplet-based reactors was performed.

Conclusions:

  • The developed microfluidic droplet-storage array provides high flexibility and freedom in droplet handling.
  • The platform is suitable for performing complex chemical and biologic reactions requiring incubation and sequential dosing.
  • This technology has significant potential for advanced applications in drug discovery and diagnostics.