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Colloidal Nanocarriers as Versatile Targeted Delivery Systems for Cervical Cancer
Abimanyu Sugumaran1, Vishali Mathialagan1
1Department of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur 603203, India.
Current Pharmaceutical Design
|June 27, 2020
Summary
Colloidal nanocarriers offer targeted cervical cancer treatment, potentially reducing side effects and improving survival rates. This approach aims to overcome limitations of conventional chemotherapy and multidrug resistance (MDR).
Area of Science:
- Oncology
- Nanotechnology
- Drug Delivery
Background:
- Cervical cancer is a leading cause of cancer death globally, particularly in developing nations.
- Conventional treatments cause severe side effects, toxicity, multidrug resistance (MDR), and poor outcomes.
- Current therapies lack specificity, damaging both cancerous and healthy tissues.
Purpose of the Study:
- To review current cervical cancer treatment challenges.
- To explore the potential of colloidal nanocarriers for targeted drug delivery in cervical cancer.
Main Methods:
- Literature review of colloidal nanocarrier applications in cervical cancer.
- Survey of various nanocarrier types including nanoemulsions, nanodispersions, polymeric, and metallic nanoparticles.
- Inclusion of photothermal and photodynamic therapy approaches.
Main Results:
- Significant advancements have been made in nanocarrier-based cervical cancer treatment.
- Various colloidal nanocarriers show promise for targeted delivery.
- The study identified key nanocarrier types and therapeutic modalities.
Conclusions:
- Colloidal nanocarriers offer potential for targeted cervical cancer treatment with reduced side effects and lower MDR incidence.
- This approach may improve patient survival rates.
- Future research should address regulatory hurdles and cost-effectiveness for clinical application.
Keywords:
Colloidal nanocarriercervical cancer targetingdrug delivery systemnanoencapsulationnanoparticlespolymeric nanoparticles
