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Cranial and Spinal Meninges

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The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
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These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...

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Updated: Dec 17, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

Tuberculum sellae meningiomas.

Stephen T Magill¹, Michael W McDermott²

¹Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, United States.

Handbook of Clinical Neurology

|June 27, 2020

Summary

This summary is machine-generated.

Tuberculum sellae meningiomas pose surgical challenges due to their location near vital structures. Understanding tuberculum anatomy aids in managing these challenging brain tumors and improving patient outcomes.

Keywords:

Endoscopic Meningioma Transcranial Transsphenoidal Tuberculum

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Area of Science:

Neurosurgery
Neuroanatomy
Oncology

Background:

Tuberculum sellae meningiomas are complex tumors.
Their proximity to critical neurovascular structures causes significant patient morbidity.
Tumor growth patterns and resulting deficits are influenced by tuberculum anatomy.

Purpose of the Study:

To elucidate the anatomical factors influencing tuberculum sellae meningiomas.
To detail preoperative evaluation, surgical approaches, and postoperative management.
To provide a comprehensive overview of managing these challenging tumors.

Main Methods:

Review of anatomical studies of the tuberculum sellae.
Discussion of preoperative workup and grading scales.
Comparison of traditional open cranial approaches versus endoscopic endonasal approaches for resection.

Main Results:

Anatomical understanding clarifies tumor growth and deficit presentation.
Surgical resection presents significant challenges.
Endoscopic endonasal approach offers an alternative to open cranial surgery.

Conclusions:

Comprehensive understanding of tuberculum anatomy is crucial for surgical planning.
Management requires careful preoperative evaluation and tailored surgical strategies.
Adjuvant therapy may be necessary for residual tumor management, impacting patient outcomes.