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Updated: Dec 17, 2025

A Free-breathing fMRI Method to Study Human Olfactory Function
Published on: July 30, 2017
Anosmia in COVID-19 Associated with Injury to the Olfactory Bulbs Evident on MRI
M F V V Aragão1,2, M C Leal3,4, O Q Cartaxo Filho4
1From the Universidade Federal de Pernambuco (M.F.V.V.A., M.C.L., M.M.V.), Recife, Brazil fatima.vascoaragao@gmail.com.
Abstract:
Patients with coronavirus disease 2019 (COVID-19) may have symptoms of anosmia or partial loss of the sense of smell, often accompanied by changes in taste. We report 5 cases (3 with anosmia) of adult patients with COVID-19 in whom injury to the olfactory bulbs was interpreted as microbleeding or abnormal enhancement on MR imaging. The patients had persistent headache (n = 4) or motor deficits (n = 1). This olfactory bulb injury may be the mechanism by which the Severe Acute Respiratory Syndrome coronavirus 2 causes olfactory dysfunction.
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