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Related Concept Videos

Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Cell Lines01:16

Cell Lines

A cell line is a population of cells grown in vitro that can be subcultured over several generations. Normal cells cease to divide after a certain number of cell divisions, a process known as replicative senescence. This number, called the Hayflick limit, was conceptualized by Leonard Hayflick in 1961 when he observed that fetal cells grown in culture could only divide 40-60 times. This limit is due to the shortening of the telomeres during each round of cell division, preventing cell division...
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...

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Related Experiment Video

Updated: Jul 6, 2026

Discrimination and Characterization of Heterocellular Populations Using Quantitative Imaging Techniques
09:48

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Author Correction: iLoF: An intelligent Lab on Fiber Approach for Human Cancer Single-Cell Type Identification.

Joana S Paiva1,2,3, Pedro A S Jorge1,2, Rita S R Ribeiro1,3,4

  • 1INESC TEC - INESC Technology and Science, Porto, Portugal.

Scientific Reports
|June 27, 2020
PubMed
Summary

An amendment to this scientific paper has been published. Please refer to the link at the top of the document for the updated version and further details.

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Area of Science:

  • This study falls within the broad area of scientific research and methodology.

Context:

  • The provided abstract does not contain sufficient information to populate this section.

Purpose:

  • The abstract mentions a published amendment, indicating a need for readers to consult the revised version.

Summary:

  • An amendment to the original paper is now available.
  • Access the updated paper via the provided link for revised content.

Impact:

  • Readers should be aware of the amendment to ensure they are referencing the latest version of the research.