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Hepatic neuroendocrine neoplasm: imaging patterns.

Abdallah de Paula Houat¹, Augusto Castelli von Atzingen², Fernanda Garozzo Velloni³

¹Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brazil.

Radiologia Brasileira

|June 27, 2020

Summary

Neuroendocrine neoplasms (NENs) are rare primary liver tumors that present diverse imaging features. Recognizing these radiological patterns is key for accurate diagnosis and identifying potential extrahepatic primary sites.

Keywords:

Carcinoma, neuroendocrine Liver Neoplasm metastasis Neuroendocrine tumors

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Area of Science:

Oncology
Radiology
Hepatology

Background:

Neuroendocrine neoplasms (NENs) are a diverse tumor group, with the liver frequently involved by metastases.
Primary hepatic NENs are uncommon but present diagnostic challenges due to varied imaging appearances.

Purpose of the Study:

To highlight the diagnostic challenges posed by primary hepatic NENs.
To discuss the radiological features that aid in differentiating hepatic NENs from other liver lesions.
To guide the investigation for extrahepatic primary sites in suspected metastatic NENs.

Main Methods:

Review of radiological presentation forms of hepatic NENs.
Analysis of imaging characteristics that suggest NENs in the differential diagnosis of liver lesions.

Main Results:

Hepatic NENs exhibit a wide spectrum of radiological appearances.
Specific imaging findings can elevate NENs in the differential diagnosis of liver lesions.
Radiological assessment can prompt the search for an extrahepatic primary tumor.

Conclusions:

Accurate radiological assessment is crucial for diagnosing primary hepatic NENs.
Understanding the diverse imaging manifestations of NENs aids in differential diagnosis.
Imaging plays a vital role in identifying primary sites for metastatic NENs.