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Sacral neuromodulation for overactive bladder in women: do age and comorbidities make a difference?
Rachel A High1, William Winkelman2, Joseph Panza3
1Department of Obstetrics and Gynecology, Baylor Scott & White Health, 2401 South 31st Street, Temple, TX, 76508, USA. Rachel.High@bswhealth.org.
International Urogynecology Journal
|June 27, 2020
Summary
Most women with overactive bladder achieve successful sacral neuromodulation implantation. Older age slightly reduces implantation odds, but comorbidities do not impact outcomes. Many patients add therapies post-implantation for improved efficacy.
Area of Science:
- Urology
- Neurology
- Medical Devices
Background:
- Overactive bladder (OAB) affects many women, impacting quality of life.
- Sacral neuromodulation (SNM) is a treatment option for OAB.
- Factors influencing SNM trial success and implantation require further investigation.
Purpose of the Study:
- To determine if patient age and comorbidities are associated with progression from SNM trial to implantable pulse generator (IPG) implantation.
- To analyze factors affecting post-implantation success and additional therapy use.
Main Methods:
- Retrospective cohort study of women with OAB undergoing SNM trial.
- Primary outcome: progression to IPG implantation.
- Multivariate logistic regression used to identify predictors of implantation and post-implantation outcomes.
Main Results:
- 91% of patients progressed to IPG implantation.
- Increasing age was associated with lower odds of implantation and post-implantation success.
- Evaluated medical comorbidities did not significantly affect implantation rates or post-implant success.
Conclusions:
- Most women experience successful SNM trials and implantation, regardless of age or comorbidities.
- Older age negatively impacts implantation odds and is linked to additional therapy use post-implantation.
- Comorbidities did not influence implantation or the need for additional therapies.
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