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Related Concept Videos

Visual Agnosia01:12

Visual Agnosia

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Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
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Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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[Unusual anisocoria].

Jan Klonner1, Daniel Salchow2

  • 1Universitäts-Augenklinik, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland. jan.klonner@charite.de.

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|June 27, 2020
PubMed
Summary

Bilateral acute iris transillumination (BAIT) syndrome, linked to moxifloxacin, causes iris depigmentation and light sensitivity. Early diagnosis aids in managing this rare condition.

Keywords:
AnisocoriaBAIT-SyndromeFluoroquinoloneIris-TransilluminationUpper respiratory tract infection

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Area of Science:

  • Ophthalmology
  • Pharmacology

Background:

  • Bilateral acute iris transillumination (BAIT) syndrome is a rare disorder characterized by iris depigmentation and muscle atrophy.
  • It is associated with moxifloxacin use, particularly after upper respiratory tract infections, and predominantly affects middle-aged women.

Observation:

  • A 53-year-old female developed anisocoria and photophobia three weeks after moxifloxacin treatment.
  • Ocular examination revealed extensive bilateral iris transillumination defects (ITD).

Findings:

  • The patient was diagnosed with bilateral acute iris transillumination (BAIT) syndrome.
  • Potential mechanisms involve antibiotic concentration in the vitreous body.

Implications:

  • BAIT syndrome can lead to complications such as persistent photophobia and secondary glaucoma.
  • Recognizing BAIT syndrome is crucial for accurate diagnosis of anisocoria, avoiding unnecessary investigations, and managing potential complications.