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Nonaesthetic Applications for Botulinum Toxin in Plastic Surgery
Matthew D Freeman1, Ilana G Margulies1, Paymon Sanati-Mehrizy1
1From the Division of Plastic and Reconstructive Surgery, Department of Surgery, Mount Sinai Hospital.
Plastic and Reconstructive Surgery
|June 27, 2020
Summary
Botulinum toxin offers diverse non-aesthetic applications in plastic surgery, treating conditions from pain to muscle disorders. Further high-quality research is needed to confirm efficacy and optimal usage protocols.
Area of Science:
- Plastic Surgery
- Medical Injections
- Regenerative Medicine
Background:
- Botulinum toxin, introduced in 1989, has expanded beyond strabismus treatment.
- Nonaesthetic applications have grown significantly across multiple surgical and medical specialties.
- This review focuses on non-aesthetic uses relevant to plastic surgeons, emphasizing evidence-based practice.
Purpose of the Study:
- To review the non-aesthetic indications of botulinum toxin in adult plastic surgery.
- To highlight evidence-based applications for plastic surgeons.
- To identify areas where further research is needed.
Main Methods:
- A comprehensive PubMed search and manual reference checking were performed.
- Articles focused on non-aesthetic uses within adult plastic surgery.
- Studies were categorized, and the quality of evidence was assessed.
Main Results:
- Botulinum toxin demonstrates potential in treating pain disorders, muscle activity issues, and hyperhidrosis.
- Applications extend to wound healing, Raynaud phenomenon, and reconstructive procedures like abdominal wall and prosthetic breast reconstruction.
- High-quality evidence from randomized controlled trials is often lacking for optimal dosing and protocols.
Conclusions:
- Botulinum toxin has established non-aesthetic roles in plastic surgery.
- Future research should prioritize high-level evidence studies to validate efficacy and refine treatment protocols.
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