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Updated: Dec 17, 2025
Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
Mean Platelet Volume is Affected in Term Fetuses with Intrauterine Growth Restriction
Gul Nihal Buyuk1, Z Asli Oskovi-Kaplan1, Aysegul Oksuzoglu1
1Obstetrics and Gynecology, Ministry of Health Ankara City Hospital, Ankara, Turkey.
Objectives:
The aim of our study was to analyze the mean platelet volume levels as a potential marker of altered placentation in intrauterine growth restriction (IUGR) cases.
Methods:
A total of 126 term singleton pregnant women with IUGR fetuses and 345 healthy pregnant controls were recruited and compared.
Results:
The mean platelet volume was significantly higher in the IUGR group (10.8±0.9 fl) than the control group (9.9±1.1 fl) (p=0.03). The mean hemoglobin was lower in IUGR group (11.3 (8.3-14.5) g/dl) than the control group (11.9 (8.2-13.0) g/dl) (p=0.04). The optimal cut-off MPV for prediction of IUGR was ≥10.55 fl, with a sensitivity of 59% and a specificity of 75%.
Conclusion:
Increased MPV levels in term pregnant women may be particularly helpful for discrimination and prediction of high-risk fetuses when IUGR is suspected.
