Ruptured Degenerating Fibroid Causing Preterm Labour and Systemic Inflammatory Response Syndrome

Area of Science:

• Obstetrics and Gynecology
• Reproductive Medicine

Background:

• Uterine fibroids affect at least 10% of pregnancies.
• Fibroids can lead to serious complications, including uterine rupture and hemorrhage.

Observation:

• A 28-year-old woman at 20 weeks gestation experienced systemic inflammatory response syndrome, acute renal failure, and massive ascites.
• These complications were secondary to a ruptured degenerated uterine fibroid.
• The event resulted in preterm delivery and neonatal death.

Findings:

• This report details a rare case of uterine fibroid rupture during pregnancy.
• The rupture precipitated preterm labor and systemic inflammatory response syndrome.
• Diagnosis was aided by imaging, and management included fertility-preserving surgery.

Implications:

• This case underscores the potential severity of uterine fibroid complications during pregnancy.
• Early diagnosis and appropriate management are crucial for maternal outcomes.
• Fertility-preserving surgical options should be considered in managing such rare events.