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Updated: Dec 17, 2025

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

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Published on: May 30, 2011

Arterial spin labeling perfusion in neonates.

Domenico Tortora¹, Mariasavina Severino¹, Andrea Rossi²

¹Neuroradiology Unit IRCCS, Istituto Giannina Gaslini, Genoa, Italy.

Seminars in Fetal & Neonatal Medicine

|June 28, 2020

Summary

Arterial Spin Labeling (ASL) reveals abnormal brain perfusion in neonates, crucial for understanding and preventing brain injury. This technique aids in assessing brain development and improving neurodevelopmental outcomes in high-risk infants.

Keywords:

Arterial spin labeling Magnetic resonance imaging Newborn Perfusion

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Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Published on: January 7, 2021

Area of Science:

Neonatal neurology
Medical imaging
Neuroscience

Background:

Abnormal brain perfusion is a primary factor in neonatal brain injury.
Understanding perfusion changes is vital for developing effective therapeutic strategies.
Arterial Spin Labeling (ASL) is a proven non-invasive method for analyzing brain perfusion.

Purpose of the Study:

To provide an overview of normal brain perfusion patterns in neonates using ASL.
To review perfusion abnormalities linked to common neonatal neurological disorders.
To highlight ASL's role in understanding neonatal brain maturation and injury.

Main Methods:

Utilizing Arterial Spin Labeling (ASL) for non-invasive brain perfusion assessment.
Reviewing existing studies on neonatal brain perfusion patterns.
Analyzing perfusion abnormalities in the context of neonatal neurological conditions.

Main Results:

ASL accurately measures brain perfusion in both term and preterm neonates.
Identified characteristic perfusion patterns in normal neonatal brain development.
Documented various perfusion abnormalities associated with neonatal neurological disorders.

Conclusions:

ASL is a reliable tool for evaluating neonatal brain perfusion.
Understanding ASL findings is key to improving therapeutic interventions for neonatal brain injury.
This technique enhances the assessment of neurodevelopmental outcomes in at-risk infants.