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Published on: July 3, 2013
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Renal kinetics in acute heart failure.
Giang Nhat M1, Nguyen Hai H2, Chau Ngoc-Hoa3
1Cardiology Department, Nhan Dan Gia Dinh Hospital, Ho Chi Minh, Viet Nam minhnhat210189@gmail.com.
Open Heart
|June 28, 2020
Summary
Worsening renal function (WRF) is common in acute heart failure (AHF), often occurring early and mild. While most patients with WRF recover during hospitalization, rapid renal recovery is infrequent.
Area of Science:
- Cardiology
- Nephrology
- Acute Kidney Injury
Background:
- Worsening renal function (WRF) in acute heart failure (AHF) presents complex mechanisms and varied prognoses.
- Understanding the characteristics and renal recovery patterns of WRF in AHF is crucial for patient management.
Purpose of the Study:
- To investigate the characteristics and renal kinetics of worsening renal function in patients with acute heart failure.
- To determine the incidence, timing, severity, and recovery rates of WRF in an AHF cohort.
Main Methods:
- Prospective enrollment of 196 patients admitted for AHF.
- Utilized European Society of Cardiology criteria for AHF diagnosis and Kidney Disease Improving Outcome criteria for WRF assessment.
- Applied Acute Disease Quality Initiative 16 Workgroup Consensus for renal recovery classification.
Main Results:
- Worsening renal function (WRF) developed in 43.4% of AHF patients, with 80.0% occurring within 48 hours of admission.
- The majority of WRF cases (89.4%) were classified as Stage 1, characterized by a median serum creatinine increase of 49.5%.
- Overall, 76.5% of patients with WRF achieved renal recovery by discharge, though rapid recovery was observed in only 20.0%.
Conclusions:
- Most instances of WRF in AHF are mild and associated with a high likelihood of recovery during hospitalization.
- Rapid renal recovery following WRF in AHF patients is not a common outcome.
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