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Related Concept Videos

Bioavailability Enhancement: Drug Permeability Enhancement01:27

Bioavailability Enhancement: Drug Permeability Enhancement

127
Body:After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt...
127

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Related Experiment Video

Updated: Dec 17, 2025

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins
11:30

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Recent advancements in liposome technology.

Nina Filipczak1, Jiayi Pan1, Satya Siva Kishan Yalamarty1

  • 1Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, MA 02115, USA.

Advanced Drug Delivery Reviews
|June 29, 2020
PubMed
Summary

Liposomes are versatile nano-sized drug delivery systems with a cellular membrane-like structure and high biocompatibility. Recent advancements focus on optimizing liposome preparation and expanding applications to novel therapies like nucleic acid and immunotherapy.

Area of Science:

  • Nanotechnology
  • Biomedical Engineering
  • Pharmaceutics
Keywords:
Cancer immunotherapyLiposomesMicrofluidicsNucleic acid therapiesRecent advancementRoutes of administration

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Last Updated: Dec 17, 2025

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins
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Background:

  • Liposomes are recognized nano-sized drug delivery systems due to their bilayer structure, ease of preparation, and biocompatibility.
  • Extensive research has focused on liposome-based systems to reduce toxicity and prolong therapeutic effects of various drug candidates.
  • Numerous FDA-approved liposomal therapeutics and ongoing clinical trials demonstrate their broad applications in anticancer, antibacterial, and antiviral therapies.