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Updated: Dec 17, 2025

A Standardized Method for the Analysis of Liver Sinusoidal Endothelial Cells and Their Fenestrations by Scanning Electron Microscopy
Published on: April 30, 2015
Imaging in Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome
Sherwin S Chan1, Antonio Colecchia2, Rafael F Duarte3
1Department of Radiology, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
Abstract:
Veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a potentially life-threatening complication of hematopoietic cell transplantation. Early diagnosis and, subsequently, earlier intervention have been shown to be beneficial to clinical outcomes. Diagnostic criteria from the European Society for Blood and Marrow Transplantation include recommendations on the use of imaging for diagnosis. This review discusses evidence on the use of imaging in the management of VOD/SOS and how imaging biomarkers can contribute to earlier diagnosis/treatment.
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