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Physicochemical and functional properties of chitosan-stabilized selenium nanoparticles under different processing
Xiaoxiao Song1, Yuying Chen1, Hongbo Sun1
1Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory for Food Quality and Safety, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Food Chemistry
|June 29, 2020
Summary
Processing affects chitosan-stabilized selenium nanoparticles (Se0NPs). Treatments like heating and freeze-drying alter aggregation, Se release, and functional properties, impacting antioxidant and antibacterial activities. Stability varies with chitosan type and processing conditions.
Area of Science:
- Materials Science
- Nanotechnology
- Biochemistry
Background:
- Selenium nanoparticles (Se0NPs) are recognized for their properties, but processing effects on their stability and function are not well understood.
- Chitosan (CS) is utilized as a stabilizer for Se0NPs, creating chitosan-stabilized selenium nanoparticles (CS-Se0NPs).
Purpose of the Study:
- To investigate the impact of various processing methods on the physicochemical stability and functional properties of CS-Se0NPs.
- To evaluate the influence of heating, freeze-drying-rehydration, and freeze-thawing on Se release, antioxidant capacity, and antibacterial activity of CS-Se0NPs.
Main Methods:
- CS-Se0NPs were subjected to different heating temperatures (37°C, 70°C, 95°C), freeze-drying-rehydration cycles, and freeze-thawing.
- Physicochemical stability (aggregation), selenium release, antioxidant capacity, and antibacterial activity were assessed for all treated samples.
Main Results:
- All tested processing methods induced varying degrees of aggregation and selenium release in CS-Se0NPs.
- Aggregation negatively impacted antibacterial activity, while increased Se release enhanced antioxidant capacity.
- High molecular weight CS (CS(H)) showed better stability than low molecular weight CS (CS(L)) during rehydration and heating, except for 95°C heating which induced rod-like triclinic Se, reducing activity.
Conclusions:
- Processing significantly alters the properties of CS-Se0NPs, influencing their stability and biological functions.
- The choice of processing method and chitosan type is critical for maintaining desired Se0NP functionalities.
- These findings offer a foundation for optimizing the application of CS-Se0NPs in various fields.
