Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

8.6K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
8.6K
Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

215
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
215

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multiplexed optoacoustic tracking and magnetic actuation of labeled blood cells in living mice.

Science advances·2026
Same author

Transcranial pulse stimulation modulates spectral signatures of Alzheimer's disease in the 3×Tg-AD mouse model.

Alzheimer's research & therapy·2026
Same author

Data-driven super-resolution optoacoustic imaging via physically encoded signal acquisition.

Research square·2026
Same author

Quantitative<i>in-vivo</i>full-waveform ultrasound tomography workflow integrating reflection imaging and resolution analysis.

Physics in medicine and biology·2026
Same author

Localization-based techniques for super-resolution imaging of vascular dynamics.

Innovation (Cambridge (Mass.))·2026
Same author

Divergent scalp-to-region distance alteration patterns in autism spectrum disorders, Parkinson's disease and Alzheimer's disease.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Dec 17, 2025

Three-dimensional Optical-resolution Photoacoustic Microscopy
08:31

Three-dimensional Optical-resolution Photoacoustic Microscopy

Published on: May 3, 2011

18.7K

Optical and Optoacoustic Imaging.

Daniel Razansky1,2, Vasilis Ntziachristos3,4

  • 1Faculty of Medicine and Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|June 29, 2020
PubMed
Summary

Optical imaging advances, including fluorescence molecular imaging and optoacoustic imaging, offer large fields of view for clinical detection. These methods visualize larger tissue areas compared to microscopy, expanding applications in surgery and non-invasive diagnostics.

Keywords:
BiophotonicsFluorescence imagingIntraoperative imagingMultispectral optoacoustic tomographyOptical imagingPhotoacoustic imagingSurgical navigation

More Related Videos

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time
09:56

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Published on: November 4, 2014

11.1K
Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

11.8K

Related Experiment Videos

Last Updated: Dec 17, 2025

Three-dimensional Optical-resolution Photoacoustic Microscopy
08:31

Three-dimensional Optical-resolution Photoacoustic Microscopy

Published on: May 3, 2011

18.7K
Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time
09:56

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Published on: November 4, 2014

11.1K
Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

11.8K

Area of Science:

  • Biomedical Optics
  • Medical Imaging Technologies

Background:

  • Optical microscopy is limited to small fields of view and superficial depths (0.05-1 mm).
  • This limits clinical applicability to niche areas like retinal optical coherence tomography.
  • There is a need for optical imaging methods with larger fields of view for broader clinical use.

Purpose of the Study:

  • To summarize progress in optical imaging methods that exceed human vision capabilities.
  • To highlight fluorescence molecular imaging and optoacoustic imaging as key technologies.
  • To discuss their potential for clinical detection and applications.

Main Methods:

  • Focus on fluorescence molecular imaging and optoacoustic (photoacoustic) imaging.
  • Comparison with optical microscopy techniques regarding field of view and depth penetration.
  • Review of recent literature and advances in technology and biomedical applications.

Main Results:

  • Fluorescence and optoacoustic imaging provide large fields of view (centimeters) in 2D/3D.
  • These methods enable visualization of larger tissue sections, crucial for clinical detection.
  • They offer wider applicability in surgery, endoscopy, and non-invasive imaging compared to microscopy.

Conclusions:

  • Fluorescence molecular imaging and optoacoustic imaging represent significant progress in optical imaging.
  • Their ability to image large tissue volumes positions them for widespread clinical adoption.
  • Continued technological and application advancements are expected in these fields.