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[One case of severely scalded patient with pneumonia and sepsis]
1Pharmacological Research, Qingdao Municipal Hospital, Qingdao 266011, China.
Abstract:
In February 2018, one 54-year-old male patient with severe scald complicated with pneumonia and sepsis was transferred to Qingdao Municipal Hospital from other hospital. Drugs including cephalosporin, vancomycin, and imipenem/cilastatin combined with ciprofloxacin were used successively for anti-infective treatment, with no obvious effect. Multiple bacterial culture results of sputum, blood, and wound exudate showed infection of extensively drug resistant Pseudomonas aeruginosa. On the 4th day of admission, the anti-infective treatment plan was adjusted, and plasma, red blood cell, and albumin were supplemented and nutritional support and symptomatic treatment were performed. At the same time, medication and drug-related adverse reaction were monitored. After treatment for more than 10 days, infection of the patient was effectively controlled and the condition gradually improved. The case suggests that severely burned patients are prone to have serious and fatal systemic infection, irregular use of antibiotics increases the risk of infection of extensively drug resistant bacteria, clear anti-infection idea and effective application of antibacterial drug can help to improve the success rate of infection treatment and are of important value in improving the prognosis of patients with severe burn.
Insights
This case study highlights a severe burn patient who developed a multidrug-resistant infection. Effective antimicrobial strategies are crucial for treating extensively drug-resistant bacteria in burn patients.
Area of Science:
- Infectious Diseases
- Critical Care Medicine
- Burn Management
Background:
- Severe burns predispose patients to life-threatening systemic infections.
- The increasing prevalence of extensively drug-resistant (XDR) bacteria poses a significant challenge in clinical settings.
- Previous antibiotic regimens failed to control the infection in this severe burn patient.
Observation:
- A 54-year-old male with severe scald, pneumonia, and sepsis presented with infection by extensively drug-resistant Pseudomonas aeruginosa.
- Initial broad-spectrum antibiotics were ineffective against the XDR pathogen.
- The patient received adjusted anti-infective treatment, supportive care, and nutritional support.
Findings:
- Effective control of the extensively drug-resistant Pseudomonas aeruginosa infection was achieved after adjusting the treatment plan.
- The patient's condition gradually improved following targeted antimicrobial therapy and comprehensive supportive care.
- Monitoring for drug-related adverse reactions was integral to patient management.
Implications:
- Irregular antibiotic use can escalate the risk of XDR bacterial infections in severely burned individuals.
- A clear anti-infective strategy and judicious use of antibacterial agents are vital for successful treatment outcomes.
- Optimizing infection control and treatment is critical for improving the prognosis of patients with severe burns.
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