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[Hyperuricemia, gout and high cardiovascular risk - how to manage them in clinical practice]

V V Fomin1, T E Morosova1, V V Tsurko1,2

  • 1Sechenov First Moscow State Medical University (Sechenov University).

Terapevticheskii Arkhiv
|June 30, 2020
PubMed

Insights

Hyperuricemia and gout are linked to increased cardiovascular disease risk. Early diagnosis and treatment with urate-lowering drugs are crucial for managing these conditions and preventing complications.

Area of Science:

  • Cardiology
  • Rheumatology
  • Internal Medicine

Background:

  • Growing evidence links hyperuricemia and gout to elevated cardiovascular disease (CVD) risk.
  • Cardiovascular complications are a leading cause of morbidity and mortality in patients with gout.
  • Current European guidelines emphasize managing high cardiovascular risk in gout patients.

Purpose of the Study:

  • To systematically examine the association between hyperuricemia/gout and cardiovascular disease.
  • To highlight the importance of diagnosing comorbidities in patients with hyperuricemia and gout.
  • To advocate for mandatory treatment strategies for high-risk individuals.

Main Methods:

  • Systematic examination of patients with hyperuricemia and gout.
  • Comorbidity assessment focusing on cardiovascular disease.
  • Review of current European treatment recommendations for gout.

Main Results:

  • Cardiovascular disease and its complications are significant comorbidities in patients with hyperuricemia and gout.
  • Patients with hyperuricemia and gout, particularly those at high cardiovascular risk, require dedicated management.
  • Urate-lowering drug therapy is essential for mitigating cardiovascular risk in this population.

Conclusions:

  • Comprehensive patient evaluation is necessary to identify cardiovascular comorbidities in hyperuricemia and gout.
  • Mandatory treatment with urate-lowering drugs is recommended for gout patients with high cardiovascular risk.
  • Adherence to the latest European guidelines ensures optimal management and reduces cardiovascular complications.

Keywords:
cardiovascular diseasegouthyperuricemiauric acid

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